Picking a laboratory freezer isn’t like buying a kitchen fridge. Get it wrong, and you could compromise samples, disrupt workflows, or blow your budget. For research labs, clinics, and diagnostic centers, the right freezer size is a cornerstone of daily operations affecting everything from sample integrity to your energy bill.
Some of the most common sizes you’ll encounter are 5 cu ft, 7–9 cu ft, and 11 cu ft models, plus larger ultra-low temperature (ULT) units. Whether you’re storing vaccines at a small clinic or banking thousands of biological samples, the capacity you choose matters.
This guide walks you through each size category, explains who they’re best for, and shares practical tips to help you match a freezer to your lab’s real needs both today and down the road.
Quick Comparison: Lab Freezer Sizes at a Glance
|
Freezer Size |
Best For |
Storage Capacity |
Key Advantages |
Things to Keep in Mind |
|
5 cu ft |
Small clinics, point-of-care testing, vaccine storage |
Limited, short-term |
Compact, energy-efficient, fits under counters |
Not ideal for growing research programs |
|
7–9 cu ft |
Mid-size labs, reagent storage, small biobanks |
Medium volume |
Flexible shelving, upright/undercounter options |
May outgrow capacity if lab expands |
|
11 cu ft |
Research centers, long-term sample storage |
High volume |
Great capacity-to-cost ratio, advanced controls |
Needs adequate floor space |
|
15–20+ cu ft |
Universities, pharma labs, large biobanks |
Very high inventory |
Built for genomics & long-term studies |
Higher cost + specialized install |
💡 Pro Tip from MediDepot: Always plan for 12–24 months of growth. Underestimating your needs is one of the most common and costly purchasing mistakes labs make.
👉 Explore Related Cold Storage & Laboratory Equipment Guides
-
Choosing the Right Medical Freezer: Laboratory & Healthcare Guide
A detailed breakdown of temperature stability, storage needs, and compliance considerations for medical-grade freezers. https://medidepot.com/blogs/article/choosing-the-right-medical-freezer-laboratory-healthcare-guide -
ULT Freezers: Features, Benefits & Long-Term Buying Tips
A deeper dive into ultra-low temperature systems for advanced research, biobanking, and pharmaceutical applications.
https://medidepot.com/blogs/article/the-complete-guide-to-features-benefits-and-buying-tips-for-long-lasting-ult-freezers -
Medical Refrigerator Locks — Optional or Essential?
Learn how security mechanisms improve sample protection, regulatory compliance, and cold storage integrity.
https://medidepot.com/blogs/article/medical-refrigerator-locks-optional-or-essential

5 cu ft Laboratory Freezers: Compact & Clinical
When square footage is tight and sample volumes are manageable, a 5-cu ft laboratory freezer shines. Think community health clinics, vaccine stations, or any setting where every inch counts.
Where It’s Used:
- CDC-compliant vaccine storage
- Short-term biological samples
- Near workstations for quick access
- Point-of-care diagnostic setups
Why Labs Love It:
- Tucks neatly under a counter
- Sips energy compared to larger units
- Recovers temperature fast after opening
Perfect For: Small clinics, urgent care centers, and labs with steady but low sample turnover.
7–9 cu ft Laboratory Freezers: The Lab Workhorse
This is arguably the most popular size range and for good reason. A 7–9 cu ft laboratory freezer strikes that sweet spot between capacity, footprint, and affordability, making it a versatile pick for many research and clinical environments.
Why It’s a Go-To:
- Comes in both upright and undercounter styles
- Shelving adapts to vials, boxes, and bottles
- Handles moderate to high weekly intake with ease
Ideal For:
- Clinical research teams
- Hospital lab departments
- Labs that store both reagents and specimens

11 cu ft Laboratory Freezers: Built for the Long Haul
When your lab deals with serious volume whether for long-term studies or high-throughput testing the 11-cu ft laboratory freezer becomes a research-ready asset.
What Makes It Stand Out:
- Ample space with multiple shelving levels
- Advanced controls for precise temperature management
- Ready to connect to alarms and data loggers
- Offers one of the best balances of capacity vs. energy use
Common Users:
- University research labs
- Diagnostic and testing centers
- Pharmaceutical R&D facilities
💡 MediDepot Tip: For 11 cu ft models, look for features like independent temperature alarms, lockable doors, and data export via USB or Ethernet key for compliance and peace of mind.
15–20+ cu ft Freezers: The Heavy-Duty Storage Solution
When you’re storing samples for years, not months, you step into the realm of 15–20+ cu ft freezers especially ultra-low temperature (ULT) units that hit –40°C to –80°C.
Typical Settings:
- Genomics and proteomics labs
- Biobanks and long-term clinical trial repositories
- High-throughput pharmaceutical research
These giants are engineered for endurance, with high-density insulation, multi-layer seals, and redundant monitoring systems to protect precious samples over the long term.
How to Pick the Right Size for Your Lab
1. Project Your Sample Volume
Match your freezer not just to what you have now, but to where your lab is headed. Research labs, especially, should plan for growth.
2. Match It to Your Application
- Vaccines → need CDC-compliant stability
- DNA/RNA → require ULT temperatures
- Tissues → do best in stable –20°C/–30°C environments
3. Measure Your Space (Really Measure It)
Check floor space, door swing clearance, undercounter height, and don’t forget ventilation needs.
4. Consider Temperature Stability
Smaller units stabilize faster, but larger models with advanced controls often handle door openings better.
5. Think Total Cost of Ownership
Bigger freezers can use more energy. Investing in an energy-efficient model can lead to significant savings over time.

Top Brand Picks from MediDepot
Below you may find some of our curated products to fit real lab needs:
- Accucold Medical Freezers – Your go-to for compact, reliable vaccine and sample storage. Digital controls, lockable door, and steady temps.
- Summit Laboratory Freezer – Built tough with adjustable shelving and fast temperature recovery. A reliable partner for mid-sized labs.
- Everest Clinical Freezer – Spacious, efficient, and uniform in temperature. Great for clinical studies that demand consistency.
- Migali Laboratory Freezer – Top-tier capacity with smart shelving, stellar stability, and advanced alarms. Made for busy research environments.
👉 Explore MediDepot's Related Catalogues
Cold Storage & Refrigeration: Discover MediDepot’s complete range of medical, laboratory, and commercial refrigeration systems designed to deliver precise temperature control, regulatory compliance, and long-term sample protection across every healthcare and research environment.
Medical / Laboratory Refrigeration: Browse our specialized selection of medical-grade refrigerators and freezers engineered for vaccine storage, biological sample preservation, and laboratory diagnostics, ensuring consistent performance and dependable cold-chain integrity.
Ice Machines & Dispensers: Explore high-efficiency commercial ice machines and water dispensers built for clinics, hospitals, and food-service areas offering reliable daily ice production, hygienic dispensing systems, and durable construction for demanding environments.
Commercial Refrigeration: Find robust commercial refrigeration solutions including reach-ins, merchandisers, prep tables, and large-capacity coolers, ideal for healthcare facilities, laboratories, and food-service operations that require consistent cooling performance.
Compact & Specialty Refrigeration: Shop compact, countertop, undercounter, and specialty refrigeration units designed for tight spaces and focused applications perfect for clinics, pharmacies, labs, and point-of-care environments with specific cold-storage needs.
Still Have Questions? We’ve Got Answers
Your freezer size shapes your lab’s daily flow and long-term potential. 5-cu ft models keep small spaces running smoothly, 7–9 cu ft freezers offer flexible performance, and 11-cu ft units deliver the capacity demanding research requires. When your work revolves around long-term, high-volume storage, larger ULT freezers become indispensable.
At MediDepot, we help labs of all sizes from neighborhood clinics to major research institutes find the cold storage that fits their science, their space, and their standards.
Frequently Asked Questions
Q1: Can a 5-cu ft lab freezer really handle clinical work?
Absolutely. It’s perfect for vaccines, common reagents, and smaller sample batches. If your lab is growing, though, you might want to size up.
Q2: Why do so many labs choose 11 cu ft freezers?
They hit a sweet spot: plenty of storage without a huge footprint, plus features that support rigorous research and compliance.
Q3: Upright or undercounter, which is better?
Upright gives you more capacity and easier access. Undercounter saves space and integrates neatly into existing workstations.
Q4: What’s most important when sizing a ULT freezer?
Focus on energy efficiency, insulation quality, and robust monitoring/alarm systems. These units are long-term investments.
*All medical and maintenance recommendations verified from official U.S. federal sources, reviewed by MediDepot Clinical Support Team.
**Disclaimer: This content is for informational purposes only and does not constitute medical advice. Always consult your physician, healthcare provider, or qualified medical professional before using any medical products or following health-related guidance. MediDepot products do not diagnose, treat, cure, or prevent any medical condition.