NEST Scientific BioFactory 1 Chamber, 2 Wide or Narrow Plug Seal Caps, Total Culture Area 647cm2, TC, Sterile, 1/pk, 8/cs

NEST Scientific BioFactory 1 Chamber, 2 Wide or Narrow Plug Seal Caps, Total Culture Area 647cm2, TC, Sterile, 1/pk, 8/cs (with 16 Sterile Wide or Narrow Vent Caps Included Separately), USP Grade VI Virgin Polystyrene, Equivalent to Corning CellSTACK® 3268, Individually Packaged in Double-Layer Sterile Bags

NEST Scientific BioFactory Systems provide a reliable, single-use multi-layer platform engineered specifically for the efficient scale-up of adherent cell cultures. Constructed from high-purity USP Class VI virgin polystyrene, these single-layer units deliver a total growth area of 647 cm² with plasma-etched tissue culture treatment to maximize cell attachment. The multi-layer structure is ultrasonically welded without adhesives or additives, eliminating leachables and extractables that cause culture abnormalities.

Designed to be dimensionally and geometrically equivalent to Corning CellSTACK® 3268 systems, they offer seamless compatibility with existing Corning accessories and automated equipment. Each flask is individually wrapped in double-layer sterile packaging and E-beam irradiated to achieve a Sterility Assurance Level of SAL 10⁻⁶. Available with either wide (26mm) or narrow (12mm) port options, these BioFactory units deliver exceptional lot-to-lot reproducibility for pharmaceutical, vaccine, and biopharmaceutical production.

Features

• Single-layer
• 647 cm² growth area
• 1 per bag, 8 units per case
• TC treated - plasma etched for adherent cells
• 2 Wide or Narrow Plug caps attached
• Also includes, 2 plug and 2 vent caps per flask, 16 total of each per case
• USP grade VI virgin polystyrene
• Sterile
• Equivalent to Corning CellSTACK® 3268

Product Details

• Individually packaged in double-layer sterile bags
• Flask layers are ultrasonically welded together without adhesives or additives. This creates a strong, gas-tight seal between layers without introducing leachables and extractables that could cause cell culture abnormalities
• Two port mouth options available. Wide mouth (26mm) ports make it easy to pour media and reach all layers of the flask. Narrow mouth (12mm) ports are designed to fit aseptic transfer caps for sterile transfer of cells and media into and out of the flasks
• Optional threaded caps are offered with chemically resistant, heat-sealable flexible TPE tubing, enabling aseptic transfer of media and cells
• Dimensionally and geometrically identical in design to Corning CellSTACK® flasks
• Compatible with Corning accessories, caps and equipment
• 100% of flasks are tested for leakage via pressure testing before shipping
• Clear lot number for batch traceability
• Suitable for large-scale cultivation of adherent cells
• Large growth area—cultivate a high volume of cells in a single operation while minimizing the risk of contamination
• Compatible with automated equipment. Especially important for larger 40-layer flasks
• Sterility Guarantee — Utilizing an imported Rhodotron® TT200 electron accelerator from Belgian IBA and an in-house irradiation facility
• Sterile to SAL 1 X 10^-6
• Extensively tested and validated for leachables, extractables, particle counts, nucleases, nucelotides, endotoxins, pyrogens, TSE/BSE etc., making Nest Biofactories suitable for end point pharmaceutical manufacturing. Full validation dossiers are available on request

Quality Details

• Manufactured in cGMP (21 CFR part 820/821) compliant factory
• Produced in ISO 13485:2016 and ISO 9001 facility
• Molded and packed in ISO 7 cleanroom
• E-beam sterilized and lot tested to SAL 10^-6
• Lot tested free of pyrogens USP 85
• Lot tested free of cytotoxins/pyrogens In Vivo USP 88 and In Vitro USP 87
• Lot tested free DNase/RNase and DNA
• Lot tested free BSE/TSE
• Certified free of animal products
• Full validation dossier available upon request

Product Specifications

Standard delivery typically takes 5-7 business days